Nafld Fibrosis Score. The associations were evaluated using multi-variable Cox regression
The associations were evaluated using multi-variable Cox regression models with restricted cubic splines. Fibrosis was scaled from 0, no fibrosis, to 4, cirrhosis. Jul 27, 2025 · The NAFLD Fibrosis Score (NFS) is a non-invasive assessment tool designed to estimate the likelihood of advanced liver scarring (stages F3-F4) in individuals with Nonalcoholic Fatty Liver Disease. The bottom line? Fibrosis-4 (FIB-4) Calculator Share The Fibrosis-4 score helps to estimate the amount of scarring in the liver. Jul 10, 2025 · Calculate the NAFLD Fibrosis Score to assess the risk of advanced fibrosis in patients with non-alcoholic fatty liver disease (NAFLD) using 6 key variables. Given risks and limitations of biopsy, non-invasive tests such as NAFLD fibrosis score, aspartate transaminase FIGURE 1 Nonlinear association between the frequency of weekly consumption of spicy foods and the risk of NAFLD/MASLD as well as liver fibrosis. NAFLD affects 25% of the population, making it the most common liver disease worldwide. 388, 0. Additionally, we analyzed genomic data based on identical fibrosis grades and compared cases with identical NAS and fibrosis scores. NAFLD, non-alcoholic fatty liver disease; MASLD, metabolic dysfunction-associated steatotic liver disease; NFS, NAFLD Fibrosis Score; FIB-4 LSM was correlated with Hui score, Forns index, fibrosis-4, and NAFLD fibrosis score (r = 0. A score <1. The NAFLD fibrosis score is a noninvasive system that uses AST, ALT, platelet count, and albumin levels to predict liver complications. If the person is at high risk of advanced liver fibrosis, refer to a hepatology specialist for further assessment and management. g. Mar 28, 2025 · The nonalcoholic fatty liver disease (NAFLD) fibrosis score is a less invasive alternative to a liver biopsy that can help predict your risk for liver damage. Learn how it works, what it means, and how it compares with other tests such as FibroScan and FIB-4. NAFLD Fibrosis Score (NFS) — an intermediate or high score (greater than minus 1. Jan 5, 2026 · Elevations in FIB-4, NFS, and APRI were associated with increased risk of severe COVID-19 in the total cohort and across various subgroups, but the FIB-4 models had the best fit based on AICs. 1, 2 Imaging Evaluation 4 days ago · Within 3 months of enrollment, participants needed biopsy-proven MASH with stage 2 or 3 fibrosis and a NAFLD activity score of 4 or higher. 001). 3 or higher suggests you may want further liver assessment There are several follow-up tests available, including measurements of liver stiffness, such as liver elastography (e. The NAFLD (Non-Alcoholic Fatty Liver Disease) Fibrosis Score estimates amount of scarring in the liver based on several laboratory tests. 459, 0. 3 indicates a low risk for significant fibrosis A score of 1. The NAFLD fibrosis score calculator identifies liver fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). 19 hours ago · Risk Stratification for Fibrosis Calculate the FIB-4 score using age, ALT, AST, and platelet count to determine risk of advanced fibrosis. 3 days ago · Simple blood test panels are commonly used to calculate risk scores, such as the Fibrosis-4 (FIB-4) index and the NAFLD Fibrosis Score (NFS). Bansal adds. This NAFLD fibrosis score calculator stratifies the degree of fibrosis to the liver in nonalcoholic fatty liver disease patients by assigning a specific stage. 3 days ago · FibroScan (vibration-controlled transient elastography) is indicated as a second-line test after initial risk stratification with simple fibrosis scores (FIB-4 or NAFLD Fibrosis Score) in patients with suspected NASH who have obesity, diabetes, or metabolic syndrome, specifically when these initial scores fall in the indeterminate range or to The secondary outcomes were ≥1-point improvement in the nonalcoholic fatty liver disease activity score (NAS), ≥1-point improvement in steatosis, ballooning degeneration, lobular inflammation scores, and fibrosis stage, improvements in NITs for fibrosis and steatosis, weight changes, and rates of serious adverse events (SAEs). Objective Liver biopsy is the most accurate method for determining stage and grade of injury in non-alcoholic fatty liver disease (NAFLD). This is a health tool that assesses the level of fibrosis, scarring of the liver, consistent with the existence of nonalcoholic fatty liver disease (NAFLD). . Nov 14, 2025 · Discover foods to avoid with fatty liver disease and how a Mediterranean diet plus C15:0 can support liver health and reduce inflammation. NAFLD activity score was scaled from 0 to 8 based upon the severity of steatosis, hepatocellular ballooning, and lobular inflammation. The nonalcoholic fatty liver disease activity score (NAS) measures disease activity by considering grades of steatosis, lobular inflammation, and hepatocyte ballooning and ranges from 0 to 8. There are several liver conditions that are defined under this term which includes steatosis which is or not accompanied by various degrees of inflammation and cannot be appointed to alcohol co Jul 27, 2025 · The NAFLD Fibrosis Score (NFS) is a non-invasive assessment tool designed to estimate the likelihood of advanced liver scarring (stages F3-F4) in individuals with Nonalcoholic Fatty Liver Disease. Compare it with a FibroScan test and other diagnostic methods for liver scarring. Fibrosis (FIB)-4 Score (FIB-4) — a score of greater than 2. 2 days ago · KHẢO SÁT CHỈ SỐ FIB-4, NAFLD FIBROSIS SCORE Ở BỆNH NHÂN GAN NHIỄM MỠ CÓ RỐI LOẠN CHUYỂN HÓA Phạm Thị Kim Dung1,2,, Lê Quang Đức1, Phạm Bình Nguyên3, Nguyễn Công Long3,4 Aims To describe the distribution of the biomarker scores Fibrosis‐4 (FIB4), nonalcoholic fatty liver disease (NAFLD) fibrosis score (NFS), and aspartate aminotransferase to platelet ratio index We aimed to validate the available indexes in NAFLD subjects and to test their ability to predict liver damage also in comparison with the NAFLD fibrosis score. 3 (<2. The NAFLD (Non-Alcoholic Fatty Liver Disease) Fibrosis Score estimates amount of scarring in the liver based on several laboratory tests. 1, 2 Jan 7, 2026 · A score less than 1. Enter the required values to calculate the FIB-4 value. Jan 12, 2026 · Every patient with mildly coarsened liver echotexture requires immediate risk stratification for advanced fibrosis using non-invasive fibrosis scores (NAFLD Fibrosis Score or FIB-4 Index), regardless of the presumed cause, because ultrasound alone cannot reliably differentiate benign hepatic steatosis from early cirrhosis. 455), suggests advanced liver fibrosis. 67 indicates high risk requiring hepatology referral. 0 if age >65) indicates low risk with negative predictive value ≥90%, while >2. It will appear in the oval on the far right (highlighted in yellow). 870, a specificity of 86%, and a sensitivity of 70%. Mar 28, 2025 · The NAFLD fibrosis score is a blood test that predicts the risk and stage of liver scarring in people with nonalcoholic fatty liver disease (NAFLD). Calculate your risk of liver fibrosis based on your age, height, weight, and laboratory test results. 422, all P < 0. COVID-19 patients frequently present with abnormal liver function tests (LFTs) and elevated non-invasive liver fibrosis scores, such as the fibrosis-4 index (FIB-4), the non-alcoholic fatty liver disease May 30, 2022 · The NAFLD fibrosis score (NFS) > 0. Aug 23, 2022 · Doctors use the NAFLD fibrosis score to predict how much scarring there is in the liver. Surrogate indexes were validated by the tracer technique (6,6-D2 -glucose and U- (13) C-glucose) in the basal state and during an oral glucose tolerance test. You can find the result interpretation and guidelines on the original study that published the score below the form. 67 suggests advanced liver fibrosis. These scores combine routine laboratory values, including liver enzymes and platelet counts, with patient age to estimate the likelihood of advanced fibrosis. 3 days ago · Abstract Background The coexistence of chronic hepatitis B (CHB) and nonalcoholic fatty liver disease (NAFLD) accelerates liver fibrosis progression, but effective noninvasive tools for fibrosis risk assessment in this specific population are lacking. METHODS: A total of 265 patients with NAFLD confirmed by ultrasonographic findings were included. Aug 23, 2022 · Learn how a NAFLD fibrosis score is calculated from a panel of blood tests and what it means for your liver health. 427, and 0. The NAFLD fibrosis score and the fibrosis-4 (FIB-4) index were used to classify the probability of fibrosis as low, intermediate and high probability. •LSM had the highest efficiency in the diagnosis of progressive liver fibrosis in NAFLD patients, with an AUC of 0. 676 was defined as progressive liver fibrosis and used to categorize the patients into T2DM without progressive liver fibrosis group (493 cases) and T2DM with progressive liver fibrosis group (93 cases). , FibroScan) and other blood-based tests, Dr. Learn when it's used, how the score is calculated, and how to interpret results.